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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CNN2
All Species:
22.12
Human Site:
Y251
Identified Species:
40.56
UniProt:
Q99439
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q99439
NP_004359.1
309
33697
Y251
S
M
S
L
Q
M
G
Y
T
Q
G
A
N
Q
S
Chimpanzee
Pan troglodytes
XP_001156976
309
33707
Y251
S
M
S
L
Q
M
G
Y
T
Q
G
A
N
Q
S
Rhesus Macaque
Macaca mulatta
XP_001110773
309
33749
Y251
S
M
S
L
Q
M
G
Y
T
Q
G
A
N
Q
S
Dog
Lupus familis
XP_854646
309
33368
Y251
S
M
S
L
Q
M
G
Y
T
Q
G
A
N
Q
S
Cat
Felis silvestris
Mouse
Mus musculus
Q08093
305
33137
Q248
D
N
S
S
M
S
L
Q
M
G
Y
T
Q
G
A
Rat
Rattus norvegicus
P37397
330
36416
G264
G
M
S
V
Y
G
L
G
R
Q
V
Y
D
P
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521357
371
41328
T291
T
I
S
L
Q
M
G
T
N
K
V
A
S
Q
K
Chicken
Gallus gallus
P26932
292
32342
M235
I
F
E
P
S
L
G
M
E
R
C
D
T
N
I
Frog
Xenopus laevis
NP_001085881
295
32821
K238
D
T
K
S
G
T
E
K
C
D
N
S
S
M
S
Zebra Danio
Brachydanio rerio
NP_998514
307
33822
Y250
T
M
S
L
Q
M
G
Y
S
Q
G
A
N
Q
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P14318
184
20172
D127
R
A
T
Y
K
H
A
D
F
K
G
P
F
L
G
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P37806
565
62709
T429
H
E
C
S
I
D
Q
T
T
I
P
S
Q
M
G
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q08873
200
22730
R143
A
N
K
K
H
T
D
R
F
P
V
L
G
P
Q
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
98
94.5
N.A.
94.8
63.3
N.A.
54.7
58.2
78.6
72.8
N.A.
23.2
N.A.
21.7
N.A.
Protein Similarity:
100
100
98.3
95.1
N.A.
95.7
74.2
N.A.
64.6
72.8
85.1
81.2
N.A.
36.5
N.A.
33
N.A.
P-Site Identity:
100
100
100
100
N.A.
6.6
20
N.A.
46.6
6.6
6.6
86.6
N.A.
6.6
N.A.
6.6
N.A.
P-Site Similarity:
100
100
100
100
N.A.
13.3
33.3
N.A.
73.3
20
20
100
N.A.
26.6
N.A.
13.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
35.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
0
0
0
0
8
0
0
0
0
47
0
0
8
% A
% Cys:
0
0
8
0
0
0
0
0
8
0
8
0
0
0
0
% C
% Asp:
16
0
0
0
0
8
8
8
0
8
0
8
8
0
0
% D
% Glu:
0
8
8
0
0
0
8
0
8
0
0
0
0
0
0
% E
% Phe:
0
8
0
0
0
0
0
0
16
0
0
0
8
0
0
% F
% Gly:
8
0
0
0
8
8
54
8
0
8
47
0
8
8
16
% G
% His:
8
0
0
0
8
8
0
0
0
0
0
0
0
0
0
% H
% Ile:
8
8
0
0
8
0
0
0
0
8
0
0
0
0
8
% I
% Lys:
0
0
16
8
8
0
0
8
0
16
0
0
0
0
16
% K
% Leu:
0
0
0
47
0
8
16
0
0
0
0
8
0
8
0
% L
% Met:
0
47
0
0
8
47
0
8
8
0
0
0
0
16
0
% M
% Asn:
0
16
0
0
0
0
0
0
8
0
8
0
39
8
0
% N
% Pro:
0
0
0
8
0
0
0
0
0
8
8
8
0
16
0
% P
% Gln:
0
0
0
0
47
0
8
8
0
47
0
0
16
47
8
% Q
% Arg:
8
0
0
0
0
0
0
8
8
8
0
0
0
0
0
% R
% Ser:
31
0
62
24
8
8
0
0
8
0
0
16
16
0
47
% S
% Thr:
16
8
8
0
0
16
0
16
39
0
0
8
8
0
0
% T
% Val:
0
0
0
8
0
0
0
0
0
0
24
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
8
8
0
0
39
0
0
8
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _